Best of the Blog: 5 Great Sources of Content for Your Blog and Email ...

Are you having trouble finding content for your blog and newsletters? This article focuses on how and where you can quickly find engaging, interesting content to can pass on to your readers and customers. Remember, the ability to regularly provide your audience with interesting, up-to-date, useful information will help keep them engaged and create opportunities to build relationships.

Finding Content for Your Blog and Email Newsletter: 5 Places

One of the biggest challenges in developing a content marketing strategy is finding content for your blog, email newsletter and other communications. And if you?re busy running your business, you may not have the time to figure out which topics will engage your audience.

Luckily, there is a host of free tools that can make finding content for your blog or email newsletter easier, regardless of the topic.

But before you start using these tools, you?ll need a list of keywords related to your hot topics. These keywords will form the basis of what you write about, improve your SEO rankings and help bring targeted leads to your website. Here are a few questions to ask when you select your keywords:

What subjects do you cover in your blog?

What keywords are your ideal customers searching for?

What words relate to your business?

Make a list of these phrases so you can refer to them during planning. Then check out these five free content sources that can inspire ideas for your email newsletters, blog posts, articles and other marketing materials:

Google Alerts: The great thing about Google Alerts is that it brings the latest articles, posts, and press releases about your favorite topics directly to you. Simply enter the keyword you wish to monitor in the search field and decide how often you want to receive notifications. You can also choose to receive updates via email or an RSS feed.

Scoop.it: Scoop.it allows you to create an online magazine about your favorite topic. Start by searching for your keyword, and Scoop.it will show you relevant content from the Web. You can select which items you want to include in your magazine. Then, you can customize it and share it with your community through social media. In addition to sharing your magazine with others, you can use the articles for inspiration for your own writing.

Alltop: Alltop pulls the best from the Web and organizes it by topic. Enter your keyword in the search box and Alltop will let you know what some of the Web?s most respected blogs have to say about it. This site is great at weeding out the junk and giving you the most relevant content.

Digg: This site shows you the top trending articles around the Internet, as chosen by its community members. You can see the most popular articles by sector such as business or lifestyle. You can also use the newswire feature to easily search for the latest articles within your sector.

Delicious: This social bookmarking site allows you to save and organize any posts or articles you find on the Web. Let?s say you plan to write some blog posts about the holiday shopping season, even if the inspiration hits you in July. With Delicious, you can bookmark and organize the Web pages you need whenever you stumble across them, so you can quickly find them when the right time comes.

Build Customer Loyalty Through Email Marketing

Stay in touch with your customers and send them offers, updates, and valuable content. With pbSmartConnections, you can easily build, track, and deploy email marketing campaigns that help grow customer loyalty.

Once you find interesting content, you can use it as inspiration. For example, if you see a great article on Alltop, you can write about the same topic from a different angle. You can even take an opposing stance on a subject to create controversy and drive people to your blog.

What?s Next:
Watch this webinar to learn how to better communicate with your customers

Source: http://www.business2community.com/content-marketing/best-of-the-blog-5-great-sources-of-content-for-your-blog-and-email-newsletters-0285646

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Daily Tips for Business: Architecture-and-Interior-Design ...

All structures requiring lighting for safety, as an architectural feature or task level lighting should use a sustainable approach achieving the required effect or satisfying the need with the least amount of energy. Modular lighting controls as discussed in this article can achieve the right combination of security, user experience and significant energy savings.

Source: http://dailytipsforbusiness.blogspot.com/2012/09/architecture-and-interior-design_25.html

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Tags: lighting

This entry was posted on Wednesday, September 26th, 2012 at 2:22 am and is filed under wow. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

Source: http://imageonenc.com/1259/daily-tips-for-business-architecture-and-interior-design/

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SUV slams into packed van in Okla., killing 7

ELMWOOD, Okla. (AP) ? An SUV veered across a highway median in the Oklahoma Panhandle early Wednesday and slammed head-on into an oncoming van full of men headed to work at a Texas meatpacking plant, killing both drivers and five of the six van passengers, authorities said.

The 2012 Chevy Suburban was moving fast and passed a couple of trucks on U.S. Highway 412 just before it crossed the center line and collided with a 2003 Ford van near Elmwood, Oklahoma Highway Patrol Trooper Betsy Randolph said. She said investigators were trying to determine whether the SUV was speeding.

"It was pretty horrific," Randolph said. "The lieutenant I talked to said he'd worked in Beaver County for 24 years, and he's never seen anything like that. When you have that many bodies involved in a crash, it's terrible."

All seven of the men in the van were from Liberal, Kan., and were headed to work at the Booker Packing Co. plant a few miles south of the Texas border in Booker, Randolph said.

The Highway Patrol said late Wednesday the van with five passengers was being driven eastbound by Alejandro Mejia Lopez on U.S. 412 when a 2012 Chevy Suburban driven westbound by Bobby Carroll Matthews crossed the center line and hit the van head-on.

Killed along with the 28-year-old Lopez were Julio Ramos Perez, 25; Rigoberto Toj Garcia, 24; Julio Cesar Don Juan Morino, 27; Sebastian Sucuquai Saquic, 21; and Juan Lorenzo, 56. Francisco Diaz, 33, was listed Wednesday night in critical condition at an Amarillo, Texas, hospital where he was airlifted.

Police said they do not know what caused the 55-year-old Matthews, of Woodward, Okla., to lose control of his vehicle.

Elmwood, in Beaver County, is less than 10 miles from the Texas state line.

Both lanes of the highway were temporarily closed but reopened about five hours later.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-09-26-Oklahoma-Deadly%20Crash/id-08d75b6212c743f6820a9af6f1ae8039

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Nike Jordan Sneakers Outlet | Reference and Education

Nike Mercurial Gasesbuy jordans created for Cristiano Ronaldo inside Gambling could be the up series of initial nike Mercurial Gases, nonetheless, this particular orginal the first is not really created
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Similar to precisely what D Lo clarify, speed is obviously the primary line of nike Mercurials. From Two thousand and two World Glass in order to The year 2010 World Glass, Nike business has used synthetic leather from the uppers
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streamlined features to make sure this particular becomes one of several most effective manufacturing football sneakers. Weighing in at merely 230g, the Mercurial Steam Several is amongst the least heavy
footwear available. New technologies includa any Fibre-composite only and also patented Steam Footing Technique that also offers enhanced traction force and luxury ? whether inside firm
or smooth soil only discs. Nevertheless the technology won?t hold on there. An shot TPU heel cover using glass-fibre put and also side to side heel coffee pods provide extra power and also
security for the rearfoot. Add any Molded Elizabeth.Versus.A new. sock-liner can cushion influence from high-speed.

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Source: http://phrenesia.com/nike-jordan-sneakers-outlet/

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Strengthen The Company With Corporate Team Building Events

Posted By: onetimearticles

In the competitive pace of modern business world, the corporate sector constantly hunts for ideas for its growth. The companies operating on this platform have a number of areas to pursue their fierce development and such areas are corporate relations both inside as well as outside the organisation. In the current state of affairs, every company believes in the mutual benefit growth system. This creates a huge demand for the PR & Media firms and corporate event organisers who can serve the companies with brilliant corporate terms building solutions and at the same time can strengthen the internal structure of the company.

The corporate team building events are the kind of occasion are mainly organized in-house. The main purpose of consolidating such activities is to increase the gelling amongst the teams. These events are planned and organized by the corporate event organizers who expertise in the field of developing fair public relations among the staff of the company. These events are generally loaded with the fun activities such as game, music and enjoyment, where people can get away with their work pressure and enjoy some leisure moments with their colleagues.

Companies generally consult the corporate team building events for the purpose of creating such event which can reflect the team building and strengthening of the entire workforce. Apart from these internal events, these Media and PR specialist agencies are also suitable for organising the meets and conferences between the companies. There are called the corporate events where the corporate minds can come together to discuss and share the new dimension of business and figure out the growth motives by meeting the requirements of mutual benefit section. Hence the trend of corporate meets and events on both internal and wider level is widely accepted and has a bright future ahead.

About the Author: For more information on corporate event organisers, check out the info available online; these will help you learn to find the corporate team building events

Article Source: http://www.articleshub.org/article/197927/Strengthen-The-Company-With-Corporate-Team-Building-Events.html

Source: http://www.articleshub.org/article/197927/Strengthen-The-Company-With-Corporate-Team-Building-Events.html

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Want Better Health? Take a Look Around You | World of Psychology

Last week, McDonald?s announcement that it will begin posting calorie counts on its menus caused an online buzz.? Reactions to the announcement ranged from support to dissent to the unconvinced.

Food choice, nutrition and diet have been growing topics hotly debated in the public arena.

But despite increased public awareness that food choice plays a vital role in health, most Americans continue to eat too few fruits, vegetables and whole grains (USDA Center for Nutrition Policy and Promotion).

The Obesity Epidemic

With more than two-thirds of American adults either overweight or obese, what American?s eat is a topic that cannot be dismissed lightly.? Studies on obesity in America have found that rates of obesity among adults has more than doubled since 1980 and that rates among children, even those as young as 2 to 5, are alarming.? Obesity rates for adolescents have tripled, while those for children aged 6-11 have quadrupled.

Along with what many have begun to refer to as an epidemic of obesity, has also come an increased focus on healthy eating behaviors and lifestyle choices.? The questions researchers and health advocates ask include: what contributes to unhealthy lifestyle choices and which interventions lead to successful behavior change, weight loss and improved health?

Education about nutrition has been finding its way into the public domain.? Magazines and newspapers, advertisements on television and information in our children?s classrooms are a few of the ways health educators have increased the knowledge of the public at large.

Environment Matters

But this fight to educate the public about a healthy lifestyle can get lost in the wealth of unhealthy products American?s encounter throughout daily life. Fast food restaurants, shopping malls, workplaces, and corner stores make eating healthy a challenge.

Not only are we surrounded by unhealthy food options, we are also surrounded by unhealthy messages about food.? The environment in which we live and work has a significant impact on what we view as healthy and on how much food we believe we need to eat.

We may not pay close attention to the billboards with coffee drinks heaped with whipped cream being consumed by happy and thin models, or commercials in which physically fit sports fans watch a game with a bucket of fried chicken, but they do have an impact on how much we believe we can and need to eat.

Effective nutrition education and behavior change requires multifaceted interventions.? Education alone has not lead to great behavior change.? Lasting change appears to require education, individual intervention and changes to our environment to make the healthy choice the easy (and obvious) choice.

Individual differences in our beliefs and attitudes about food have an impact on what and how much we eat, but so does our environment.? The people around us, the messages we see at work, on TV and in our communities and, yes, even information about the calories in a Big Mac can have an impact on the food choices we make.

If we want better health, we may need to change how we think about food; increasing your awareness about how your environment influences your thoughts about food is one place to start.

References:

Whitaker RC, Wright JA, Pepe MS, Seidel KD, Dietz WH. Predicting Obesity in Young Adulthood from Childhood and Parental Obesity. New England Journal of Medicine, 37(13):869?873, 1997.

8 Serdula MK, Ivery D, Coates RJ, Freedman DS. Williamson DF. Byers T. Do Obese Children Become Obese Adults? A Review of the Literature. Preventive Medicine, 22:167?177, 1993.

Christy Matta M.A. is a trainer, consultant and writer. She is the author of "The Stress Response: How Dialectical Behavior Therapy Can Free You from Needless Anxiety, Worry, Anger, and Other Symptoms of Stress."

Christy has worked in mental health since 1994, is intensively trained in Dialectical Behavior Therapy(DBT) and has extensive training in Mindfulness. She is an experienced group leader and trainer in both Mindfulness and DBT Skills Groups. Christy blogs regularly for Psych Central at Dialectical Behavior Therapy Understood.

Like this author?
Catch up on other posts by Christy Matta, MA (or subscribe to their feed).

????Last reviewed: By John M. Grohol, Psy.D. on 25 Sep 2012
????Published on PsychCentral.com. All rights reserved.

APA Reference
Matta, C. (2012). Want Better Health? Your Eating Environment Matters. Psych Central. Retrieved on September 26, 2012, from http://psychcentral.com/blog/archives/2012/09/25/want-better-health-your-eating-environment-matters/

?

Source: http://psychcentral.com/blog/archives/2012/09/25/want-better-health-your-eating-environment-matters/

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Guild Wars 2, and the Player Dynamic of Online Gaming | Double Crit

So, lately I?ve been playing?Guild Wars 2?(It?s awesome and you should try it out if you haven?t already, by the way). A funny thing happened to me the other day. I can?t recall exactly what I was up against, ?but after a certain point in my early wanderings, my luck ran out ? I couldn?t take them all on, and my last stand was?less than glorious. I was dead.

A random player happened upon the area: I?d never seen him before, and we?d never had any prior affiliation. He proceeded to slaughter the foes which ended my life. Just as I was about to return to a waypoint, he paused, turned, and revived me, then continued on his merry way without so much as a word.

This sort of thing, I?ve come to learn, is normal in the game world- even if it?s ?tacitly unusual in pretty much every other MMO on the face of the planet. Curious, isn?t it?

My first experience with an MMO, like many, was with?World of Warcraft. The players there were a mixed bag. On the one hand, it was possible to occasionally come across a Good Samaritan ? the horde player who helped you out with a quest, the high-level alliance player who let you go on your merry way instead of ganking you. On the other hand?those people were increasingly rare as you moved up the ranks. It was more frequent on a PVP server to find yourself at the mercy of some angry manchild than it was to have someone actually help you on your way, and I actually found myself being cussed out once because someone found out I played both factions.

Even players within the same faction seemed to often prefer to do things on their own, isolated within their little cliques. True, there was a real sense of community within guilds, but at the same time, it was a very individualistic setting, which very much gave the vibe of ?every player for themselves. You?re on your own unless you can find someone to attach yourself to.

He seems rather cross.

It?s even worse in purely competitive games- but we?ve beaten that horse almost to death here, so I?m going to leave that statement standing.

Guild Wars 2?is?different. A reviewer on Forbes?mused that it honestly played like the developers took a list of everything people disliked about MMOs, then made a conscious effort to get rid of the elements on that list. Arenanet has consciously shunted almost every long-standing tradition in MMO history, and the game?s all the better for it.

Players are actually rewarded for helping one another out, and I?m not talking organized, well-oiled guild raids here (another staple of the genre).?The traditional quest system (which lent itself very well to a ?me first? mentality, along with spawn camping), has been thrown violently out the window. Everybody gets credit for every quest, so long as they participate in its completion. As a result, the mentality has completely shifted from competition to participation. Well, except in the PVP arenas?but that?s another story.

What does this mean? What, if anything, does it say about us as gamers? Is it just a case of similar people gravitating towards similar environments, or is there something more going on beneath the surface? Could it be that the developer of a game subtly influences the attitudes and actions of the players with every design choice they make? That perhaps?the League of Legends?community is so hateful due in part to a conscious (or unconscious) decision on Riot?s part?

Could it be that human beings are, in truth, actually hard-wired to cooperate, and it?s only when placed into an environment that awards competition that they begin to squabble?

Maybe it?s just that?Guild Wars 2?s?environment doesn?t lend itself very well to player cruelty, and as a result, toxic players have far greater difficulty spreading their poison to others. ?You know how it goes ? all it takes is one bad apple, and pretty soon you?ve a whole rotten, worm-ridden barrel of filth. Perhaps it?s a combination of the sorts of people the play environment appeals to as well as active prevention on the part of Arenanet itself.

It?s hard to say -?there?s no straight, simple answer to this quandary, and I?ve neither the resources nor the time to execute a scientific study into the matter.?Ultimately, this post is just a bit of food for thought. Next time you?re online, pay attention to how you act ? and how others behave around you. Your attitudes might be influenced in more ways than you know.

Image Credits:?[Guild Wars 2 Guide] [Armed Gamer] [Gamer Zines]

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Source: http://doublecrit.wordpress.com/2012/09/25/guild-wars-2-and-the-player-dynamic-of-online-gaming/

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Tokyoflash releases the Kisai Logo, treads the line between confusing and amazing (video)

Extraordinary Japanese watchmaker Tokyoflash adds to its line of outlandish timepieces with the Kisai Logo. Much like its brethren, its face can't be easily read by the uninitiated, with a block representing hours running around digitally displayed minutes. Wrapped in a classy stainless steel and colored acetate, it's got an EL backlight for use in the dark and a hidden binary mode for demonstrating your intellectual credentials. Like the company's other devices, it's available for the first 48 hours of its life for $99 (€78 or £63) before September 27th, when prices increase to $139 (€110, £88) and you can find plenty of explanatory details in the video after the break.

Continue reading Tokyoflash releases the Kisai Logo, treads the line between confusing and amazing (video)

Filed under: Wearables

Tokyoflash releases the Kisai Logo, treads the line between confusing and amazing (video) originally appeared on Engadget on Tue, 25 Sep 2012 03:00:00 EDT. Please see our terms for use of feeds.

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/l4rOoRypCLw/

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Fuel Fix ? Auto industry revs up for race to meet fuel standards

A federal mandate to slash the nation?s fuel demand has refiners bracing for a sales hit. But automotive and petrochemical engineers are heading into overdrive to create gas-saving technologies.

New fuel economy targets require auto makers to nearly double the average miles per gallon of passenger vehicles, hitting 54.5 by 2025. That means cars and trucks that Americans buy in 13 years will be smaller with turbo-charged engines and more assisted-driving features that cut back on trips to the gas pump, industry analysts say.

From Ford?s EcoBoost engine to Chrysler?s nine-speed transmission, auto companies are working to make their cars and trucks more fuel efficient. That?s bad news for the nation?s refineries, which already have seen demand for their petroleum products drop more than 10 percent since 2006.

The decline is expected to continue. Some industry leaders say gasoline demand in the United States peaked several years ago and will fall for the foreseeable future. Refineries have closed in Pennsylvania and the U.S. Virgin Islands in recent years.

?You can?t just take away 20 to 40 percent of your market and expect these things to run,? said Charles Drevna, president of the trade organization American Fuel & Petrochemical Manufacturers.

?If these things come to pass, I think there is going to have to be another look at how economic these refineries can be,? he said.

?Toughest challenge?

Drevna said he?s skeptical that the auto industry will hit the aggressive federal targets. Manufacturers are challenged to turn the gas guzzlers that Americans historically have liked into fuel sippers, without sacrificing safety, cost and performance.

?It?s fair to say that the challenge they are facing now will be the toughest challenge they have ever faced,? said Gary W. Rogers, president and CEO of FEV Inc., which engineers power trains and other auto systems.

To help meet the challenge, auto makers are turning to the petrochemical industry. Plants on the Gulf Coast and elsewhere process natural gas liquids that become the light-weight plastic alternatives to heavy steel auto parts. The lighter a vehicle, the less energy is needed to propel it down the road.

?It?s one of the most exciting times to be in automotive,? said Steve Henderson, president of Dow Automotive. Auto companies ?need science that only companies like Dow can deliver,? he said.

Integrating several metal auto parts into one plastic component can cut the weight by as much as half, Henderson said.

Though plastic can do the job of steel with less mass, it carries a heftier price tag. For instance, carbon fiber parts have debuted in higher-end vehicles, but now there?s a push to make them affordable in family vehicles.

?Every product that we make now has a focus on reducing mass,? Henderson said. ?It?s that fundamental of a change.?

Despite the growing popularity of hybrids and alternative-fuel vehicles, finding ways to reduce fuel consumption in conventional petroleum-driven cars and trucks is key, industry analysts say.

Last week, the International Energy Agency reported that existing technology could cut the world?s fuel consumption in half by 2030. The internal combustion engine using petroleum, however, will still hold at least 80 percent of the auto market then, IEA leaders said.

Given a surge in the sale of cars and trucks in emerging economies like China, the auto industry and policy makers must act fast to curb the growing global demand for petroleum, said Richard Jones, deputy executive director for the IEA.

?We cannot afford to wait for electric or hydrogen solutions,? Jones said. ?Without such action, the transport energy demand will reach unsustainable proportions.?

Reducing the size and weight of conventional cars and trucks isn?t the only method that is moving auto makers toward the fuel efficiency goals.

The cars of the future will have engines that pack more power into each cubic inch. Three- and four-cylinder engines will be typical, reducing energy-wasting friction and weight from under the hood.

?It?s a lower-cost way to get better fuel economy than going to a hybrid,? Rogers said.

Nine-speed transmissions are expected to emerge as soon as next year, allowing vehicles to get closer to optimal engine power at every speed.

Automated driving

Cars and trucks will provide more automated driving as well, to reduce fuel-wasting driving habits, such as engine idling and heavy braking, said Andrew Smart, director of industry relations for SAE International, an engineering association.

Technology that turns off the engine when at a red light or gradually slows a car as it approaches heavy traffic can add up to significant fuel savings.

?I don?t know if we will get to 50 miles a gallon or not, but I think we will incrementally improve the fleet average over time,? said Greg Garland, CEO of refining and petrochemical giant Phillips 66. ?You will see technology continue to push the barriers and the frontiers of efficiency.?

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Source: http://fuelfix.com/blog/2012/09/24/auto-industry-revs-up-for-race-to-meet-fuel-standards/

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Romney: "I used to think that becoming rich and becoming famous would make me happy. Boy was I right." (Americablog)

Share With Friends: | | Politics - Top Stories Stories, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/250511261?client_source=feed&format=rss

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Cheeky! Sofia Vergara Tweets Her Wardrobe Malfunction

Sofia Vergara's dress ripped during the Emmys -- and she shared the damage with her followers! Plus, check out more stars' cute, candid and crazy Twitter photos

Source: http://www.ivillage.com/celebrity-twitter-pictures/1-b-229669?dst=iv%3AiVillage%3Acelebrity-twitter-pictures-229669

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Elimination and also Treatment pertaining to Acne scarring ...

While that might sound elementary, the initial place to begin with acne scar tissue therapy is elimination.

Most people cannot predict after these people can have an zits outbreak as effectively as exactly how severe that outbreak are gonna be. If an individual experience zits outbreaks, having a very great precautionary treatment routine can become a positive way to keep zits minimized, reducing the chance regarding scarring initially. It will be as washing the hands to help you avoid spreading germs. Follow the links in this article for more information on www.microdermabraisionexfoliation.com.

Among just about all with the factors that will give go up to zits outbreaks, heredity is portion of the blend. Additionally, heredity plays an element inside the number of skin damage you can acquire from acne, or in other words, your capability for that you heal.

Almost all acne sufferers will develop some sort of scarring damage, from slight in get to significant. The previously inside living that acne breakouts cure is opened way up, the much more likely scarring are going to be decreased.

Acne scarring is the conclusion result of the system?s therapeutic process. The decrease associated with elastic fibers inside skin color combined along with thickened collagen groupings that grow overly help along with scar tissue. Follow the links in this article for more information on skin care.

There tend to be two kinds of surgical mark:

Hypertropic Scars would end up being the solid and stained scarring that show above the standard floor of your skin layer.

Keloid scars are usually discolored scars on the skin level or below and expand outward in the initial injury just like a stretch indicate.

There are usually several treatment options available in reducing as well as eliminate the noticeable signs involving scare tissue from zits.

Topical Remedies ? A number of topical remedies are available. These gels are placed on your damaged place and are designed to hydrate the skin as well as remove deceased skin color cells, which allows pertaining in order to epidermis cell rejuvenation along together with replenishment, reducing or even eliminating the design associated with scars. Follow the links in this article for more information on younger looking skin.

Silicone Bed sheets ? Contemporary research has shown that silicone is an effective cure in scar tissue removing. While the science of how it works isn?t entirely understood, several companies make silicon sheets and also silicon based remedies that can decrease or get rid of the visual appeal of scarred tissues.

Microdermabrasion : Throughout microdermabrasion, a dermatologist works in the handheld buffing steering wheel and an unique abrasive ointment to remove the outer lining layer from the pores and skin. When the particular brand-new skin color grows in, it is healthier and offers a lot more elasticity compared to aged skin, reducing or even eliminating the actual visible indications associated with scarring. Follow the links in this article for more information on microdermabraision treatment.

Chemical Peels ? A new chemical peel runs upon the chemical substance solution involving Phenol, Trichloroacetic Acid, and Alphahydroxy acids to remove the actual outer layers associated with damaged pores as well as skin. Similar for you to microdermabraision and also laser beam resurfacing, new skin tissue exchange the taken off of ruined cells, reducing or reducing the visible indicators involving scarring.

Laser Resurfacing ? Performed by your certified cosmetic cosmetic surgeon, a targeted lazer can be targeted around the remedy area. As the particular laser electricity penetrates skin, it vaporizes the lake plus the surface area stratum of pores and skin, leaving the more significantly cellular levels untouched. Laser resurfacing in addition really assists to bring back the elasticity in the actual epidermis by shortening your collagen fibers which have been in the actual pores and skin layers, reducing or reducing the particular visible signs regarding scarring. Follow the links in this article for more information on younger looking skin.

Always be confident to be able to consult a brand-new skin doctor before going through along with treatment with regard to scare tissue. However, all of these sort of treatments have been shown for you to be successful, so once you obtain the right 1, it will be only a matter of time prior to skin damage is diminished or eliminated!

Please visit our website http://www.zimbio.com/SkinCare+treatments%2C+Acne%2C+Anti+Aging%2C+SkinCare+Products/articles/m9NKGuJWina/Remove+blackheads+whiteheads+Microdermabrasion?add=True for more information about microdermabraision treatment.

Source: http://articlepdq.com/health-fitness/elimination-and-also-treatment-pertaining-to-acne-scarring/

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Arab Online Content on the up Despite Low Penetration Levels ...

Analyst Insight by An Hodgson, Technology, Communications and Media Analyst at Euromonitor International

As the number of Internet users expanded by 167% over 2006-2011 in the Middle East and North Africa region, the demand for Arabic-language online content has risen in parallel. Click to Tweet! Although the capability of writing right-to-left and setting up technologies that adhere to Arabic is a challenge for the region, online businesses can stand to benefit by targeting a large non-English speaking market, while consumers can gain access to services they were excluded from previously by language barriers.

Internet Users and Internet User Penetration in Selected Arab Countries: 2011

Source: Euromonitor International from International Telecommunications Union/OECD/national statistics/UN

• With a population of around 421 million people in 2011 and the vast majority speaking Arabic, the Middle East and North Africa region remains a market of untapped potential for online businesses. Online marketing companies, ?sellsumers?, social networks and retailers are increasingly looking to provide Arabic content;
• However, although major companies such as Google and Twitter have committed to Arabic, the Arabic-content segment remains underdeveloped, held back by low regional Internet penetration levels, few Arabic online creative start-ups and a lack of IT talent. The largest Arabic Internet user nation, Egypt, had 23.2 million Internet users in 2011, yet an Internet user penetration rate of only 22.4% of the population.

Implications

Arabic content has not been able to keep up with technological progress, although emerging markets and interest among a tech-savvy Arabic youth are driving businesses to invest in the segment:

• A large Arabic youth populace, especially in North Africa, presents strong opportunities for the online sector, which is typically driven by younger users. The increasing proliferation of smartphones means low-income persons, such as students or the unemployed youth, need no longer have a PC to access the web. The development of Arabic content apps is an underserved market with strong growth potential;
• However, the development of Arabic content remains expensive and time-consuming, as the language is much harder to programme and input than English. Consequently, only major companies are able to finance the switchover, led by the likes of Google, Facebook, Yahoo and Twitter, which have all launched Arabic versions over 2010-2012;
• Despite major technological leaps and huge capital investment in telecoms, especially in the Middle East, there is not enough Arabic content available to take advantage of new broadband networks, with consumers not feeling the need for a high-speed broadband connection. This restricts consumer take-up and the return on infrastructure investment. The Middle East and North Africa region saw capital investment of US$36.7 billion in telecoms in 2011;

Internet Users and Capital Investment in Telecoms in the Middle East and North Africa Region: 2006-2011

Source: Euromonitor International from International Telecommunications Union/OECD/national statistics

• The Arab Spring movement, which took place over 2010-2012, has been pivotal in driving more Arabic users to social media, news networks and digital platforms. However, the dominance of English on the web has meant that it is mainly the educated, urban, middle and upper classes that have come online, limiting users from the large rural and lower-income markets. Increasing Arabic content online can thus help penetrate the Middle East and North Africa`s 116 million rural population, as of 2011;
• A lack of entrepreneurial talent, low levels of IT literacy and technological expertise in Arab countries, and the vicious cycle of not enough users online developing Arabic content and not enough content in Arabic to push Internet penetration rates are major factors impeding expansion in the Arabic online segment. Nonetheless, economic growth, increasing incomes and educational levels in the Middle East and North Africa region will likely see Arabic a growing competitor to English in the online domain.

Prospects

• The Middle East and North Africa region is forecast to see a 54.7% increase in Internet users over 2012-2020, in part as a consequence of the increasing availability in Arabic content. Click to Tweet! Growing demand for mobile Arabic-language platforms, especially for banking and retail services, will drive the regional m-commerce sector, providing opportunities for businesses in the online domain;
• Arabic-based content will be driven by Middle Eastern telcos going forward, as companies such as UAE-based Etisalat and du, and Kuwait-based Zain increasingly rollout more Arabic mobile apps and value-added services aimed at retaining subscribers in competitive markets. The UAE saw the largest total telecom revenues in the Arab world in 2011, at US$16.4 billion;
• While Arabic content will continue to face barriers such as the popularisation of English-language sites, low IT literacy and increasing but low Internet user levels, local governments will likely be key in making Arabic available on the web. eGovernment portals have been launched by most Arab countries as of mid-2012, attracting citizens through Arabic content and convenience.?

Source: http://blog.euromonitor.com/2012/09/arab-online-content-on-the-up-despite-low-penetration-levels.html

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France gives initial green light to EU fiscal pact

PARIS (Reuters) - French President Francois Hollande's Socialist-led government kickstarted ratification on Wednesday of a European Union budget discipline pact it grudgingly accepts as the next step out of the euro zone debt crisis.

Prime Minister Jean-Marc Ayrault's cabinet gave initial approval to the fiscal compact agreed in March by Hollande's predecessor Nicolas Sarkozy and 24 other European leaders, which requires euro zone countries to slash their public deficits or face sanctions such as fines.

The cabinet's green light paves the way for official parliamentary ratification next month, despite noisy dissent within Hollande's left-leaning coalition and growing public disenchantment with the European Union. With unemployment running at a 13-year high, French voters are hostile to the prospect of further prescribed austerity.

Acknowledging the reservations of many left-wing legislators, Ayrault appealed to the Socialists and their parliamentary allies to back the bill and save the government the embarrassment of relying on Sarkozy's conservative UMP party.

"There are still waverers and those who are hostile ... My objective, and the government's, is to convince the highest number possible," Ayrault told a news conference.

"Parliament's approval, which I hope will be massive, will give even more force to the president's voice in European negotiations."

To sweeten the pill - and to try to take the sting out of a series of planned street protests against the pact - the government will present a bill to parliament on October 2 alongside a package of EU-wide growth measures secured by Hollande at his first EU summit in June.

Nonetheless, some Socialists are likely to break ranks over a bill seen as a reminder of Sarkozy's close links with German Chancellor Angela Merkel and his support for Berlin's demands for austerity in Europe.

"We don't like this pact, it is a Sarkozy legacy," said Elisabeth Guigou, head of parliament's foreign affairs committee and one of the senior Socialists tasked with rallying the coalition behind the accord. "But you don't have to love a pact to ratify it. It's one part of a deal and just the first step."

POLITICAL COST

The pact is seen as the latest small step towards resolving Europe's sovereign debt crisis after Germany's constitutional court this month gave the go-ahead to a permanent bail-out fund and pro-European parties came out top in a Dutch election.

But the passage of the bill will carry a political cost for Hollande at home and does nothing to forestall a looming clash with EU paymaster Germany over the deeper measures Berlin believes are needed for euro's longer-term survival.

Even if it does not change the outcome, a vote against the accord by some left-wingers and ecologists within Hollande's coalition will be a political embarrassment just as surveys show a steady decline in support for him since his election in May.

"The public is falling out of love with the European Union," European Affairs Minister Bernard Cazeneuve conceded on Tuesday, a day after a survey showed nearly two-thirds of voters would now reject the 1992 Maastricht Treaty that led to the euro.

France's top court has said the new budget rules do not require any change to the constitution, meaning Hollande can skip a referendum which he would not be certain of winning.

The EU budget pact enters into force either when 12 out of the 17 euro zone countries ratify it, or on January 1 next year. Half a dozen, including Germany, have already backed it.

To set an example of fiscal responsibility, Hollande has promised to find 30 billion euros ($39.17 billion) of savings in the 2013 budget to shave France's public deficit to 3 percent of gross domestic output next year en route to a fully balanced budget by the end of his five-year mandate.

Yet economists question how he can achieve such savings without dragging the economy into recession. The 2013 budget is due to be unveiled on September 28.

There is also potential for more upsets further down the line, with French officials already warning they may struggle to sell German plans for much closer European integration to an austerity-fatigued French public.

"It would not be sensible to launch into talks on a new treaty before we have got out of the crisis. It will be possible when there is not this sense of a risk of the euro zone falling apart, when Greece and Italy are back on track," said Guigou.

"The big issue right now is ensuring that Europe does not slip into recession."

(Additional reporting by Catherine Bremer, Emmanuel Jarry, Yves Clarisse, Marc Joanny; Writing by Mark John and Daniel Flynn; Editing by Catherine Evans)

Source: http://news.yahoo.com/france-gives-initial-green-light-eu-fiscal-pact-112025410--finance.html

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Language of ancient Egyptians translated

A 37-year project to compile a dictionary of an ancient Egyptian script used for daily communication has been completed, offering an unprecedented look at the words of ordinary ancient Egyptians.

The Chicago Demotic Dictionary, so named because it was created by University of Chicago researchers, translates Demotic Egyptian, the tongue of common Egyptians from about 500 B.C. to A.D. 500.

Demotic was used in everyday Egyptian documents and letters, said Janet Johnson, a University of Chicago Egyptologist. The researchers compiled the words in the dictionary from Demotic on stone carvings, papyrus and broken fragments of pottery.

"Personal documents (letters, tax receipts, accounts, legal texts, etc.), administrative documents, and literary, scientific and religious texts were all written in Demotic and provide a wealth of information about the Egyptian-speaking population in Egypt," Johnson told LiveScience in an email.

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The language was a prominent one during Greek and Roman occupation of Egypt in this period. Along with hieroglyphs and Greek, Demotic is one of the three languages on the famous Rosetta Stone, which helped early Egyptologists first decipher the formal hieroglyphic script.

The hardest parts about compiling a Demotic-to-English dictionary included reading the script itself, which is derived from picturelike hieroglyphs but is in cursive, Johnson said. As in English, Demotic words can also have multiple meanings, so the researchers had to differentiate between primary and secondary definitions.

"One of the major challenges has been that, through time, we have decided to include more and more information, meaning that the project has taken much longer than originally anticipated," Johnson said.

The dictionary is available online. The idea, Johnson said, is that scholars can use the dictionary to translate and publish unpublished Demotic texts, as well as to do work on contemporary languages.

"The dictionary will be very useful, as there are more unpublished documents in Demotic than any other phase of ancient Egypt," James Allen, a Brown University Egyptologist, said in a statement.

Demotic survives today in a few English words, including "adobe," the Demotic word for brick, which was picked up by Arabic speakers and later became part of the Spanish language. The word "ebony" also has Demotic roots.

Follow Stephanie Pappas on Twitter @sipappas or LiveScience @livescience. We're also on? Facebook and Google+.

? 2012 LiveScience.com. All rights reserved.

Source: http://www.msnbc.msn.com/id/49092627/ns/technology_and_science-science/

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Motorola?s RAZRi Has a Whopping 2GHz Intel Processor [Motorola]

Calling it their "biggest launch since the original RAZR" (no sniggering in the back row, please), Motorola's RAZRi is the first phone with a 2GHz Intel processor; however good that may be. Sounds impressive though, non? More »

Source: http://feeds.gawker.com/~r/gizmodo/full/~3/UCxyIwD5tNk/motorolas-razri-has-a-whopping-2ghz-intel-processor

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Algeria Launches International TV Channel ... - Morocco World News

By Larbi Arbaoui

Morocco World News

Taroudant, September 18, 2012

In a move to strengthen Algeria?s international outreach, Numidia News has launched the testing phase of its international news channel Numidia News TV on the Nilesat satellite.

In anticipation of the official launch of its programing, the channel is broadcasting a medley of programs, interviews and recent speeches by world leaders, which have been collected by reporters of the channel all over the world, including an exclusive interview with Saad Eddin Al Othmani, the Moroccan foreign minister, about Morocco?s reaction to the amateurish film that sparked rage in the Islamic world and its standpoint towards the Syrian crisis.

According to the administration of Numidia News, the channel is led by the same staff of the agency in charge of the website of Numidia News, whereas the office of Numidia News in Washington is responsible for coordinating between offices all over the world.

Numidia News TV can be accessed on the Nilesat satellite at 11602.85MHz, pol.H SR:27500 FEC:3.

In an exclusive statement, Mr. Samer Riad, general manager of the channel, said that the channel crew consists of Algerian journalists who have previously worked in foreign channels and newspapers.

It is worth mentioning that the TV channel has already set up offices in most North African countries except Morocco. But it seems that the channel?s biased political agenda concerning the Sahara issue may block the channel from establishing an office in Rabat.

While Morocco?s neighbor, known for its explicit support to the Polisario separatists, is working hard to build international media corps, Morocco, unfortunately, is still depending on ineffective local TV channels that don?t meet the needs of Moroccans, let alone contribute to building Morocco?s positive image at the international level.

For many years, Moroccan journalists and analysts living overseas have been calling on the Moroccan government to revamp its channels so that they can cope with international standards, thus, reaching a worldwide viewership. These calls have so far fallen on a deaf ears. During his trip to Washington D.C, Mustapha El Khalfi, minister of communication and government spokesperson, said that the government had set out to launch an international channel in four languages. So far his promise has not been? materialized, nor was he able to open offices for the three Moroccan channels, Al Oula, 2M and Medi1 TV in major world capitals.

Source: http://www.moroccoworldnews.com/2012/09/56869/algeria-launches-international-tv-channel-rabat-asleep-2/

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132 tunnel out of Mexico prison near US border

Adriana Alvarado / AP

A group of Mexican federal police stand in front of the prison in Piedras Negras, Mexico, late Monday.

By NBC News staff and wire reports

MEXICO CITY -- More than 130 inmates escaped through a tunnel from a Mexican prison on the border with the United States in one of the biggest jailbreaks the country's beleaguered penal system has suffered in recent years.

Homero Ramos, attorney general of the northern state of Coahuila, said 132 inmates of the Cereso prison in the city of Piedras Negras had escaped through the tunnel in an old carpentry workshop, then cut the wire surrounding the complex.

---

Corrupt prison officials may have helped the inmates escape, said Jorge Luis Moran, chief of public security in Coahuila, adding that U.S. authorities had been alerted to help capture the fugitives if they try to cross the border.

Eighty-six of the escaped prisoners were serving sentences or pending trials for federal crimes, including drug trafficking, the Zocala newspaper reported. The rest faced state charges, it said.

Many challenges for incoming president
The jailbreak is a reminder of the challenges that await Enrique Pena Nieto, the incoming president, who has pledged to reduce crime in the country after six years of increased gang-related violence under President Felipe Calderon.

Many of Mexico's prisons are overcrowded and struggle to counter the influence of criminal gangs that can use their financial muscle to corrupt those in charge.

Ramos said that the state government of Coahuila was offering a reward of $15,700 for information leading to the capture of each fugitive.

Mexico's drug war: No end in sight

The Piedras Negras complex housed a total of 734 inmates, and the tunnel through which the prisoners escaped was about four feet wide, 9 1/2 feet deep and 23 feet long, Ramos said.

Piedras Negras is about 150 miles southewest of San Antonio, Texas.

Money, drugs, guns and gangs: Child actors shame Mexico politicians with mockumentary

Mass breakouts
There have been numerous mass breakouts in the last few years from Mexico's penal system, and prison officials are frequently accused of complicity with drug cartels.

A video "mockumentary" that shows children as kidnappers, corrupt cops and drug traffickers sparked a fierce debate in violence-torn Mexico. Msnbc.com's Dara Brown reports.

At the end of 2010, more than 140 inmates escaped a prison in the border city of Nuevo Laredo. This February, at least 44 people died in a fight between rival gangs at an overcrowded prison in northern Mexico.

More on this story from NBC's San Antonio affiliate WOAI.com

Pena Nieto has pledged to reform the prisons, though experts say he will struggle to make an impact unless he combines this with root-and-branch reform of the justice system.

Pena Nieto, 46, of the centrist Institutional Revolutionary Party, will take office in December. The party was widely accused of corruption during its long rule between 1929 and 2000, and he has promised to break with that checkered past.

More Americas coverage on NBCNews.com

Gang violence
Northern Mexico has been hit particularly hard by violence stemming from brutal turf wars between drug gangs that have overshadowed Calderon's conservative administration.

Calderon has used the military to try and crack down on the gangs, and has captured or killed many of the top drug lords.

President: Mexico gang-related deaths fall by 15 percent in 2012

But his efforts have come at a price.

Mexico's drug war is also part of a drug culture with roots in music, movies and even religion

Gang-related violence has surged on Calderon's watch, and fighting between cartels and their clashes with security forces have claimed more than 55,000 lives over the past six years.

Last week the Mexican Navy captured one of the biggest kingpins active near the U.S.-Mexican border, the leader of the Gulf Cartel, Jorge Costilla, known as "El Coss."

Complete World coverage on NBCNews.com

Analysts forecast this would lead to an increase in criminal activity in northern Mexico as rival gangs fought for control of lucrative smuggling routes in the area.

Reuters and WOAI.com contributed to this report.

More world stories from NBC News:

Follow World News from NBCNews.com on Twitter and Facebook

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Source: http://worldnews.nbcnews.com/_news/2012/09/18/13932142-132-inmates-tunnel-out-of-mexico-prison-near-us-border?lite

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GENWI Nabs $2M From Mike Maples, Roger McNamee To Help Publishers Go Mobile

While magazines and newspapers have slowly made the transition from print to digital, they're still coming to grips with mobile. For publications (big and small) to survive amidst the industry's declining ad revenues, it's imperative for publishers to be able to push their content on every available platform, particularly tablets, the device that's really best suited to consuming digital content. Founded in 2010, GENWI has developed a cloud publishing solution and mobile Content Management System (mCMS) that gives publishers an easy way to re-purpose their content and create engaging mobile apps. The startup's platform provides templates and tools that make it easy for both small and enterprise publishers to customize both native and HTML5 apps and push their content out across those devices. Based on this functionality, the platform has attracted publishers like Conde Nast, IndiaTimes, Forbes, PBS Kids and The Hollywood Reporter, and is today receiving further validation of its model from Mike Maples and Roger McNamee, who are investing $2 million in the startup, bringing its total funding to $7.1 million.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/S0ZZGV1gIjc/

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Oil near $96 after BOJ eases monetary policy

BANGKOK (AP) ? Oil rose to nearly $96 a barrel after two days of declines as Japan's central bank joined the U.S. Federal Reserve in easing monetary policy.

The Bank of Japan announced it was moving to protect the country's fragile recovery by extending its monetary easing by increasing its asset-purchasing fund to 55 trillion yen ($700 billion) from 45 trillion yen, to counter the Japanese yen's rise. That followed moves by the U.S. Federal Reserve to stimulate growth through so-called quantitative easing.

Benchmark oil for October delivery was up 63 cents to $95.92 per barrel at midday Bangkok time in electronic trading on the New York Mercantile Exchange. The contract fell $1.33 to close at $95.29 on the Nymex on Tuesday.

Brent crude added 46 cents to $112.49 on the ICE Futures exchange in London.

The move by the Japanese central bank boosted stock markets in Asia. Japan's benchmark Nikkei 225 briefly touched 9,277.47 ? its highest intraday level since May 2.

Traders were also keeping their eyes on oil supplies as U.S. Gulf Coast refineries returned to production after shutting down due to Hurricane Isaac.

"We're getting back a few more refineries post Issac, but on the flip side a few refineries had some restart issues and a few are headed into maintenance," said Carl Larry of Oil Outlooks and Opinions in a newsletter.

Brent dropped $1.76 to $112.03 a barrel in London on Tuesday. Reports that Saudi Arabia is keeping production high to drive oil prices lower may have pressured Brent, which is the benchmark for many international crudes.

In other futures trading in New York, wholesale gasoline rose 2.5 cents to $2.834 per gallon. Heating oil gained 1.7 cents to $3.144 per gallon. Natural gas fell 0.7 cents to $2.766 per 1,000 cubic feet.

___

Follow Pamela Sampson on Twitter at http://twitter.com/pamelasampson

Source: http://news.yahoo.com/oil-near-96-boj-eases-monetary-policy-051224902.html

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Subscriber data from Internet service providers

Companies that provide Internet access services have released their earnings reports for the latest quarter. There are subscriber figures and other data from selected Internet service providers:

? July 19: Verizon Communications Inc. gained just 2,000 broadband customers in the latest quarter ? the worst result in four years. Verizon says the weak showing was in part due to Verizon ending the sale of DSL connections to people who don't have a landline phone account. The effort is part of an attempt to improve profitability. Verizon has upgraded part of its phone network with optical fiber, a service it sells as FiOS. It has raised prices, also to improve profitability, resulting in fewer new FiOS subscribers ? 134,000 during the quarter, to end with 5.1 million.

? July 24: AT&T Inc. says it gained 553,000 U-verse Internet customers to end the quarter with 6.5 million. That helped offset losses in customers who get DSL, a slower and older technology.

? July 25: AOL Inc. says it had 3 million access subscribers as of June 30, down 84,000 during the quarter.

? July 31: Frontier Communications Corp. says it added 5,442 broadband customers to end with 1.78 million.

? Aug. 1: Comcast Corp. says it added 156,000 high-speed Internet customers during the second quarter to end with 18.7 million.

? Aug. 2: Time Warner Cable Inc. says it added 59,000 high-speed residential customers to end the quarter at 10.8 million.

? Aug. 7: Charter Communications Inc. added 37,000 broadband customers to end with 3.8 million.

Cablevision Systems Corp. added 25,000 high-speed customers to end with 3 million.

? Aug. 8: CenturyLink Inc. says it added 18,000 high-speed Internet customers to end with 5.76 million.

? Aug. 9: Windstream Corp. says it lost broadband subscribers for the first time. They were down 2,200 to 1.36 million. Bigger phone companies, which are focused on larger markets, have been losing DSL subscribers for some time to cable, a phenomenon that now appears to be spreading to Windstream's territory.

Source: http://news.yahoo.com/subscriber-data-internet-providers-161133168--finance.html

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Swedish doctors claim pioneering uterus transplant

STOCKHOLM (AP) ? Doctors in Sweden say they have performed the world's first mother-to-daughter uterus transplants "without complications."

Specialists from the University of Goteborg on Tuesday said two women received wombs from their mothers in surgical procedures on Sept. 15 and 16.

The university said one recipient had her uterus removed many years ago due to cervical cancer and the other was born without a uterus. Both women are in their 30s.

Team leader Mats Brannstrom said both "are doing fine but are tired after surgery. The donating mothers are up and walking and will be discharged from the hospital within a few days."

Turkish doctors last year said they performed the first successful uterus transplant, giving a womb from a deceased donor to a young woman.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/bbd825583c8542898e6fa7d440b9febc/Article_2012-09-18-Sweden-Uterus%20Transplant/id-527b83bc0b494dd19dcd73d70d571a94

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Scientists discover mutations associated with skin disorder (DSAP)

ScienceDaily (Sep. 16, 2012) ? A Chinese research team, led by Anhui Medical University and BGI, has found strong genetic evidence of a link between mutations of the mevalonate kinase gene (MVK) and disseminated superficial actinic porokeratosis (DSAP). It is a major step toward discovering the genetic pathogenesis of DSAP, and sheds light on its further molecular diagnosis and treatment.

The latest study was published online in Nature Genetics.

DSAP is a rare, non-cancerous, non-contagious skin disorder that causes dry, itchy lesions on the arms and legs. It usually begins to develop in adolescents and reach near-complete penetrance by the third or fourth decade of life. The accumulated sun exposure is a risk factor for DSAP. DSAP is a chronic disorder; it can be treated, but it cannot be cured.

In this study, Chinese researchers performed exome sequencing in two affected and one unaffected individuals who belong to a DSAP family. Through variants analysis and data filtering, they supposed that MVK gene emerged as the only candidate gene located in previously defined linkage region linked to DSAP. Then they confirmed the co-segregation between the identified novel deleterious mutation and DSAP phenotype within the family.

To further identify novel MVK mutations, researchers conducted Sanger sequencing in other DSAP cases, which identified additional novel deleterious mutations. And none of which was detected in 676 unrelated and ethnically matched controls. It provided strong evidence that these novel mutations were not polymorphisms. They did not find MVK mutations in other clinical subtypes of Porokeratosis, suggesting that MVK mutations may be specific to DSAP patients.

Mevalonate kinase, the protein encoded by MVK, is an important enzyme in the mevalonate pathway that is vital for multiple cellular processes by providing cells with essential bioactive molecules. In the investigation of the impact of MVK expression on the biological activities of keratinocytes, researchers indicated that MVK plays a role in regulating calcium-induced keratinocytes differentiation and the MVK expression could protect keratinocytes from UVA-caused apoptosis.

Tao Jiang, senior scientist of this project at BGI, said, "Considering the high genetic heterogeneity of DSAP, It is fortunate for us to find the causative gene MVK by sequencing only three exomes and using previous genome-wide linkage results. Our study provides new insights into the pathogenesis of DSAP, and the identified MVK mutations offer the best candidate targets for gene diagnosis and clinical treatment of the disease."

Xuejun Zhang, corresponding author of this study, President of Anhui Medical University, said, "The exome sequencing is an effective method for identifying disease gene of monogenetic diseases in recent years. In this study, the Chinese scientists found disease gene MVK for DSAP using exome sequencing plus functional study. It not only indicates China has step into the most advanced level in searching the disease genes for monogenetic disease in the world, but also provides scientific basis for revealing DSAP pathogenesis, genetic counseling, risk prediction, prenatal diagnosis, new drug development, clinical diagnosis and treatment."

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Story Source:

The above story is reprinted from materials provided by BGI Shenzhen, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Sheng-Quan Zhang, Tao Jiang, Min Li, Xin Zhang, Yun-Qing Ren, Sheng-Cai Wei, Liang-Dan Sun, Hui Cheng, Yang Li, Xian-Yong Yin, Zheng-Mao Hu, Zhen-Ying Wang, Yuan Liu, Bi-Rong Guo, Hua-Yang Tang, Xian-Fa Tang, Yan-Tao Ding, Jian-Bo Wang, Ping Li, Bao-Yu Wu, Wen Wang, Xiang-Feng Yuan, Jun-Sheng Hou, Wei-Wei Ha, Wen-Ju Wang, Yu-Juan Zhai, Jing Wang, Fang-Fang Qian, Fu-Sheng Zhou, Gang Chen, Xian-Bo Zuo, Xiao-Dong Zheng, Yu-Jun Sheng, Jin-Ping Gao, Bo Liang, Pan Li, Jun Zhu, Feng-Li Xiao, Pei-Guang Wang, Yong Cui, Hui Li, Sheng-Xiu Liu, Min Gao, Xing Fan, Song-Ke Shen, Ming Zeng, Guang-Qing Sun, Yu Xu, Jing-Chu Hu, Ting-Ting He, Ying-Rui Li, Huan-Ming Yang, Jian Wang, Zhong-Yi Yu, Hui-Feng Zhang, Xin Hu, Ke Yang, Jie Wang, Shi-Xiang Zhao, You-Wen Zhou, Jian-Jun Liu, Wei-Dong Du, Li Zhang, Kun Xia, Sen Yang, Jun Wang, Xue-Jun Zhang. Exome sequencing identifies MVK mutations in disseminated superficial actinic porokeratosis. Nature Genetics, 2012; DOI: 10.1038/ng.2409

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/7YPGkABTprc/120916160931.htm

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